CRA

pH Value

Little Pro on 2016-01-13 Views:  Update:2019-03-10

pH value measures how acidic or basic a substance is. It measures the activity of hydrogen ions in a substance or solution and it is typically approximated as the concentration of hydrogen ions. pH value ranges from 0 to 14.

A pH of 7 is neutral (for example, pure water). A pH less than 7 is acidic, and a pH greater than 7 is basic. Chemicals that are very basic or very acidic are corrosive. They can cause severe burns.

You can often find it in the section 9 of a safety data sheet (SDS).

Regulatory Implications of pH Value

pH is an important factor to consider before conducting any toxicology studies. Strong acids or bases are corrosive to bio-membranes and do damages to tissues. They are naturally acutely toxic. Acute toxicity studies (including skin corrosion, eye irritation, sensitisation and 28d repeated dose toxicity studies) should be avoided for corrosive substances with high pH values (pH>=11.5) or low pH values (pH<=2).

Under GHS, a chemical should be considered as Skin Corrosive Category 1 if it has a pH<=2 or >=11.5 in the absence of other info.

More Physicochemical Properties

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 Tags: Topics - CRAPhysiochemical Property

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